BOSTON (Interstat) — The Boston Celtics host the Philadelphia 76ers on Saturday in a matchup of Eastern Conference rivals at TD Garden. The Celtics enter with a 59-29 record, while the 76ers are 49-40. Boston is a 7.5-point favorite, with an over/under of 206.5, according to Interstat’s game simulator, which projects a 121-109 Celtics victory. The teams have met 10 times this season, with Boston holding a 6-4 edge. However, Philadelphia won the most recent meeting Thursday, 106-93, behind guard Tyrese Maxey’s 30 points, two rebounds and five assists. Joel Embiid added 19 points, 10 rebounds and eight assists, and Paul George scored 23 for the 76ers. Maxey has been a focal point in the series, averaging 26.3 points over the last six matchups against Boston. In his past 10 games overall, he has scored at least 21 points each time, including a 32-point, eight-rebound, five-assist outing April 10 against Indiana and a 31-point, six-assist performance April 15 against Orlando. In the series, Maxey recorded 31 points, four rebounds and six assists in a 100-108 loss April 24, and 29 points and nine assists in a 111-97 win April 21. For Boston, forward Jayson Tatum has been a consistent two-way force. In the Celtics’ loss Thursday, he had 17 points, 11 rebounds and three assists in 29 minutes. Over his last five games, Tatum has averaged 22.2 points, 11.8 rebounds and 6.8 assists. He recorded a 30-point, seven-rebound, 11-assist triple-double in a 128-96 win over Philadelphia on April 26, and had 25 points, 11 rebounds and seven assists in a 123-91 victory April 19. In the April 28 loss at home, Tatum posted 24 points and 16 rebounds. The series has been marked by wide swings. Boston won 128-96 on April 26 and 123-91 on April 19, while Philadelphia countered with 113-97 and 111-97 victories. The 76ers have won two of the last three meetings in Boston, including Thursday’s result. Overall, the teams have split the four games at TD Garden this season, with each winning twice. Philadelphia enters with wins in four of its last five games overall, including victories over Milwaukee, Indiana and Orlando. The 76ers lost at Houston 113-102 on April 9. Boston has won five of its last six, with the only loss coming Thursday to the 76ers. The Celtics defeated Orlando, New Orleans, Charlotte and Toronto in that span, along with a 128-96 blowout of Philadelphia. Key matchups include Maxey against Boston’s perimeter defense, which has struggled at times to contain his penetration. Tatum will face a Philadelphia front line led by Embiid and George, though the 76ers have often used multiple defenders on him. The over/under of 206.5 reflects a series that has produced both high-scoring affairs — four games exceeded 210 points — and defensive struggles such as Thursday’s 199-point total. Tipoff is scheduled for 7:30 p.m. Eastern. The game will be broadcast nationally on ESPN.