CHARLOTTE, N.C. (Interstat) — A surging Virginia team riding a five-game winning streak will face a Duke squad looking to cap a resurgent season when the Cavaliers and Blue Devils meet in a neutral-site clash at Bank of America Stadium on Saturday. The Cavaliers (10-2) enter with their highest win total in years, fresh off a dominant 27-7 victory over rival Virginia Tech. Their defense has been a cornerstone, allowing an average of just 16.2 points during their current streak. Quarterback Chandler Morris has provided steady leadership, coming off a game where he accounted for 207 total yards and a touchdown against the Hokies. Duke (7-5) has shown explosive potential, averaging 40.3 points in its last three contests. The Blue Devils are led by dynamic quarterback Darian Mensah, who is coming off a 268-yard, two-touchdown passing performance in a 49-32 win over Wake Forest. Mensah has accounted for 11 touchdowns (8 passing, 3 rushing) in his last four games. Virginia won the regular-season meeting in Durham on Nov. 15, 2025, by a score of 34-17, holding Duke’s offense in check. The Cavaliers will aim for a repeat defensive performance, while the Blue Devils seek redemption and an eighth win to solidify their bowl resume. According to National Statistical’s game simulator, Virginia is projected to win 31-24. However, oddsmakers list Duke as a 4-point favorite with an over/under of 57.5 points, indicating expectations for a high-scoring affair. The game kicks off at 3:30 p.m. EST on Saturday, Dec. 6, 2025.