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Preview: Astros at Cubs – Saturday, May 23, 2026 CHICAGO (Interstat) — The Houston Astros and Chicago Cubs continue their three-game series Saturday afternoon at Wrigley Field, with first pitch scheduled for 1:20 p.m. local time. The forecast calls for 63-degree temperatures and cloudy skies. Houston (21-31) enters the game after a 4-2 victory over the Cubs on Friday, snapping a three-game losing streak. The Astros have yet to announce their starter, listing either right-hander Colin Rea (4-2, 3.12 ERA) or right-hander Kai-Wei Teng (2-3, 4.50 ERA) as the probable pitcher. Rea has been more effective this season, while Teng has struggled with command. Chicago (29-22) leads the National League Central by three games despite dropping the series opener. The Cubs will counter with a starter to be determined, though their bullpen remains a strength. Right-hander Ethan Roberts, who threw two scoreless innings Friday, has been a reliable option out of the pen. Over his last five appearances, Roberts has allowed one earned run in 8 2/3 innings. Players to watch Astros right-hander Spencer Arrighetti has been dominant in recent starts. He earned the win Friday, scattering two hits over five scoreless innings with five strikeouts. Over his last five outings, Arrighetti is 4-1 with a 0.96 ERA and 27 strikeouts in 30 innings. He has not allowed a run in his last 12 1/3 innings. For the Cubs, center fielder Pete Crow-Armstrong provided the only offense Friday with a two-run home run. He is batting .267 with six homers and 24 RBIs. Roberts, who has not allowed a hit in his last four outings covering 7 innings, is a key setup man for closer Adbert Alzolay. Recent form Houston has lost seven of its last 10 games, including a series defeat at Minnesota earlier in the week. The Astros rank near the bottom of the American League in runs scored, averaging 3.8 per game. The Cubs had won four of five before Friday’s loss. Their pitching staff owns a 3.45 ERA, fourth-best in the National League. Chicago is 16-9 at Wrigley Field this season. Head-to-head Friday’s 4-2 win was Houston’s first in five meetings with Chicago this year. The Astros held the Cubs to two hits, both singles aside from Crow-Armstrong’s homer. Arrighetti’s start was the fourth time in the last five games a Houston pitcher allowed one earned run or fewer. Projection Interstat’s game simulator projects a 3-2 Astros victory. The game will be the second of four between the teams this weekend, with the series concluding Sunday. Both clubs have Monday off before starting road trips.

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