Preview: Cardinals at Marlins, April 22, 2026 MIAMI GARDENS, Fla. (Interstat) — The St. Louis Cardinals and Miami Marlins will look to break a series deadlock when they conclude a three-game set Wednesday at loanDepot Park. First pitch is scheduled for the evening under cloudy skies with a temperature around 78 degrees. The Cardinals (13-9) evened the series with a 5-1 victory Tuesday after dropping the opener 5-3 on Monday. St. Louis has won seven of its last 10 games. Miami (11-12) seeks to regain momentum before embarking on a lengthy West Coast road trip. The pitching matchup features right-handers seeking different outcomes. St. Louis will start Kyle Leahy (2-2), while Miami counters with Janson Junk (0-2). A player to watch for the Cardinals is right-hander Michael McGreevy, who took the loss Monday despite a solid start. Over his last five outings, McGreevy has been inconsistent but brilliant at times, including a six-inning, no-hit performance against Tampa Bay on March 28. For the Marlins, right-hander Max Meyer is a key figure. He earned the win Monday against St. Louis, striking out eight over 5 1/3 innings. In his last start against the Cardinals, he allowed three hits and two earned runs. Offensively, St. Louis shortstop Masyn Winn drove in a run in Monday’s loss. The Cardinals’ bullpen, including Matt Svanson, who threw 1 1/3 scoreless innings Monday, has been a strength. Miami’s late-inning relievers, Andrew Nardi and Pete Fairbanks, helped secure Monday’s victory. According to National Statistical’s game simulator, the projected final score is St. Louis 6, Miami 3. Despite this, sportsbooks have installed Miami as a pregame favorite with a spread of -1.5. The over/under for total runs is set at 8.5. Following the game, the Cardinals return home to open a series against the Seattle Mariners on Friday. The Marlins begin a three-city trip Friday in San Francisco.