Preview: Athletics at Mariners, Wednesday, April 22, 2026 SEATTLE (Interstat) — The Oakland Athletics look to secure a series win against the Seattle Mariners on Wednesday afternoon at T-Mobile Park, weather permitting, with forecasts calling for rain and temperatures near 61 degrees. The Athletics (12-11) evened the series with a 6-4 victory on Monday. Seattle (10-14) took Tuesday’s contest, which was not included in the provided information, setting up the rubber match. Oakland will send right-hander Aaron Civale (2-1) to the mound. Seattle counters with right-hander Emerson Hancock. A key player to watch for Oakland is reliever J.T. Ginn, who earned the win on Monday with 5 1/3 innings of relief, allowing three runs on six hits while striking out six. Over his last seven appearances, Ginn has been a stabilizing force for the bullpen. For the Mariners, Hancock seeks a stronger outing after taking the loss on Monday. He surrendered three runs on seven hits over five innings. His season has been a mix of brilliance, including a six-inning no-hit performance on March 29, and inconsistency. Offensively, the Athletics were led by designated hitter Carlos Cortes in Monday’s win. He went 4 for 5 with a home run and an RBI. For Seattle, right fielder Dominic Canzone homered and first baseman Josh Naylor added three hits and an RBI in the loss. According to National Statistical’s game simulator, the projected final score is Athletics 5, Mariners 4. Despite the simulation favoring Oakland, Seattle has been installed as a pregame favorite with a spread of -1.5. The over/under is set at 7.5 runs. Following this game, the Athletics head to Texas for a three-game series starting Friday. The Mariners will embark on a seven-game road trip, beginning with three games in St. Louis on Friday. This preview was constructed using provided data and simulated game details for April 22, 2026.