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Preview

Preview: Padres at Pirates, Wednesday, April 8, 2026 PITTSBURGH (Interstat) — The Pittsburgh Pirates look to secure a series win when they host the San Diego Padres in the rubber match of a three-game set Wednesday at PNC Park. First pitch is scheduled for 6:35 p.m. EDT under cloudy skies with a game-time temperature near 39 degrees. The series is split after a contrasting two games. The Padres shut out the Pirates 5-0 on Monday before Pittsburgh responded with a 5-1 victory Tuesday. The Pirates (6-4) will send right-hander Mitch Keller (1-0) to the mound. Keller earned a win in his first start of the season, tossing 4 1/3 scoreless innings with six strikeouts against Cincinnati on March 31. He will be opposed by Padres right-hander Michael King (0-1). King took the loss in his season debut against San Francisco on March 31, allowing four earned runs over three innings. A player to watch for San Diego (5-5) is right-hander Germán Márquez, who dominated the Pirates on Monday. He pitched five scoreless innings, allowing six hits and striking out four in the victory. For Pittsburgh, right-hander Bubba Chandler will look to rebound after a tough outing against these same Padres on April 6, when he surrendered three earned runs in 4 1/3 innings. According to National Statistical’s game simulator, the projected final score is Pirates 5, Padres 4. Despite the projection, San Diego has been installed as a pregame favorite with a spread of -1.5. The over/under is set at 7.5 runs. Following Wednesday’s game, the Padres return home to open a four-game series with the Colorado Rockies on Thursday. The Pirates have an off-day Thursday before beginning a six-game road trip Friday with three games against the Chicago Cubs.

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